Báo Cáo Một Trường Hợp Ngộ Độc Asen Cấp Tính Được Trị Thành Công Tại Bệnh Viện Nhi Trung Ương

Pham Thi Thanh Tam, Phan Viet Hai, Nguyen Thi Nga, Duong Dinh Cua, Nguyen Thi Mai

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Tóm tắt

Arsenic is a poisoning metallic element, in which trivalent inorganic arsenic compounds are considered unique. Children can be exposed from arsenic containing water, food and folk remedies with unclear ingredients [1]. The main toxic mechanism of As3+ is inhibition of the pyruvate dehydrogenase (PDH) complex, which leads to decrease in acetyl-CoA production, decrease in cellular respiration and free oxygen radical (0-) and hydrogen peroxide (H202) are born, which make cytotoxic. Arsenic poisoning causes damage to multiple organs: keratosis of the skin, nail and squamous cell cancer, neuropathy, repolarization of the myocardium, liver damage and subsequent sequelaes [1], [2]. Arsenic poisoning has no specific symptoms, so it is easy to overlook, especially in children [2]. The epidemiological exploitation and history of poisoning drugs are very important to avoid missing arsenic poisoning. We report a case of successfully treated arsenic poisoning at the Vietnam National Children’s Hospital.

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