Clinical and Paraclinical Characteristics of Chlamydia Trachomatis Pneumonia in Infants Less than 6 months of Age at National Children’s Hospital

Pham Thu Hien, Vu Thi Tam, Nguyen Thi Thanh Thuy, Nguyen Tan Hung, Nguyen Thi Thanh Phuc, Do Thi Xuan

Main Article Content

Abstract

Objectives: The study aim was to describe clinical and paraclinical characteristics of Chlamydia trachomatis pneumonia in children under 6 months of age at Vietnam National Children’s Hospital.


Methods: This cross-sectional study included 71 cases of C. trachomatis pneumonia in Respiratory Department, Vietnam National Children’s Hospital between 1 September 2017 and 31 August 2018.


Results: Important features of C. trachomatis pneumonia in children under 6 months of age include persistent cough, nasopharyngitis, conjunctivitis, history of vaginal birth, mother’s history of vaginosis during pregnancy. Absolute eosinophil counts greater than 300/mm3 may suggest C. trachomatis pneumonia.


Conclusion: Clinical manifestations of pneumonia due to C. trachomatis pneumonia are persistent cough, nasopharyngitis, conjunctivitis, mother’s history of vaginosis during pregnancy. A higher than 300 eosinophils/mm3 is strongly associated with C. trachomatis pneumonia.

Article Details

How to Cite
Thu Hien, P., Thi Tam, V., Thuy, N. T. T., Hung, N. T., Phuc, N. T. T., & Xuan, D. T. (2020). Clinical and Paraclinical Characteristics of Chlamydia Trachomatis Pneumonia in Infants Less than 6 months of Age at National Children’s Hospital. Journal of Pediatric Research and Practice, 4(3). https://doi.org/10.25073/jprp.v4i3.190

References

[1] Who, Pneumonia: The Deadliest Childhood Disease Pneumonia, World pneumonia day infographic, November 2015.
[2] Who, Hospital care for children. Guidelines for the management of common childhood illnesses, Second edition, 2013.
[3] Edna Lucia Souza, Renata Silva Girão, Juçara Magalhães Simões et al., Chlamydia trachomatis: A major agent of respiratory infections in infants from low-income families, Jornal de Pediatria - Rio J, 2012.88(5).
[4] Kamal Narain Mishra, Pankaj Bhardwaj, Anuradha Mishra et al. Acute Chlamydia Trachomatis Respiratory Infection in Infants, Journal of Global infectious diseases, Jul-Sep. 3(3) (2011) 216-220.
[5] Ranit Mishori, Erica L, Mc Claskey et al., Chlamydia Trachomatis Infections: Screening, Diagnosis, and Management, American Family Physician 86(12) (2012), December 15, 2012.
[6] Chun-Jen Chen, Keh-Gong Wu, Ren-Bin Tang et al. Characteristics of Chlamydia trachomatis infection in hospitalized infants with lower respiratory tract infection, Journal of Microbiology, Immunology and Infection 40 (2007) 255-259.
[7] Le Van Duc, Pham Thi Minh Hong. Characteristics of pneumonia in children under 6 months old infected with Chlamydia Trachomatis at the Respiratory Department of the Children’s Hospital No. 2. HCMC Medical Journal. Vol 18, Addendum of No. 1, 2014 (in Vietnamese).
[8] Mohan Pammi, R. Margaret, Hammerschlag (2018), Chlamydia trachomatis infections in the newborn. BioMedCentre Infectious Diseases, 2014, pp. 14 - 20.
[9] Eszter Balla, G. Gilbert, G. Donders, Fruzsina Petrovay et al., Chlamydia trachomatis Infections in Neonates. Journal of Medical Microbiology, March 66 (2012) 1114-1117.
[10] Marcela López-Hurtadol, Fernando M Guerr, Early Neonatal Infection by Chlamydia trachomatis, Journal of Infectious Diseases & Therapy. 2(5) (2014).
[11] K. Terada, Kishimoto, T. Niizuma et al., A case of Chlamydia trachomatis and Mycoplasma pneumoniae coinfection in a child. Kansenshogaku Zasshi, 1999 Sep. 73(9) (1999) 939-42.