Prevalace of Cushing’s Syndrome and Investigate Plasma Coctisol Levels in Children with Steroid Resistant Nephritic Syndrome

Duong Thi Thanh Binh, Nguyen Thu Huong, Truong Manh Tu, Nguyen Thi Linh, Nguyen Phu Dat

Main Article Content

Abstract

Objectives: to determine the prevalance of Cushing’s syndrome and investigate plasma cortisol levels in children with SRNS. Subjects: 182 children with SRNS at Vietnam National Children’s Hospital from June 2018 to July 2019 were invoved in the study. Methods Descride and crossesional study. Results: The prevalence of Cushing syndrome in children with SRNS was 37.4%, mainly in man (78%) and the group of children from 2 to 10 years old. Duration of using corticoid below 5 years had the prevalance of Cushing syndrome was 27.2%. Low plasma cortisol levels in children with Cushing syndrome accounted for 60.3%, markedly low when children with changes in body shape as round face (100%), weight gain (91.2%), cetral fat (94.1%) and hirsutism (82.4%). Conclusion: children with SRNS had a high rate of Cushing’s syndrome, mainly in boys and ages from 2 to 10 years old. Plasma cortisol levels decreased clearly in 2 children with Cushing’s syndrome with changes in body shape or round face, weight gain, central fat, hirsutism.

Article Details

How to Cite
Binh, D. T. T., Thu Huong, N., Manh Tu, T., Thi Linh, N., & Phu Dat, N. (2020). Prevalace of Cushing’s Syndrome and Investigate Plasma Coctisol Levels in Children with Steroid Resistant Nephritic Syndrome. Journal of Pediatric Research and Practice, 4(3). https://doi.org/10.25073/jprp.v4i3.188

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